منابع مشابه
Studies on human platelet gangliosides.
Gangliosides, glycosphingolipids which contain sialic acid, were studied in human platelets. They represented 0.5% of the platelet lipids and accounted for 6% of the total neuraminic acid content of platelets. Three major ganglioside fractions were identified and characterized. Ganglioside I was hematoside (G(6)) and comprised 92% of the platelet gangliosides. It contained glucose, galactose, a...
متن کاملStudies on human platelet proteins.
D URING the last ten years evidence has been presented from different laboratories that fibrinogen may not be essential for thrombin-mediated platelet aggregation.14 Although the presence, in platelets, of a thrombinsensitive protein other than fibrinogen has been reported from this laboratory and also by other workers,5 #{176} there is no report of its isolation, structure, physicochemical pro...
متن کاملStudies on human platelet protease activity.
SOLUBILIZED PROTEIN DERIVED FROM HUMAN PLATELETS WAS FRACTIONATED BY DEAE CELLULOSE COLUMN CHROMATOGRAPHY AND ANALYZED FOR PROTEASE ACTIVITY USING THREE SUBSTRATES: denatured bovine hemoglobin, alpha casein, and purified plasminogen-free human fibrinogen. A protein fraction was found with proteolytic activity which was heat labile and not attributable to plasmin. The activity was not potentiate...
متن کاملGangliosides of human kidney.
Five gangliosides isolated from human kidney have been characterized. The two main fractions were shown to be typical extraneural gangliosides in having lactose as their neutral carbohydrate moiety. Their structures were identified as: AcNeu(alpha2-3)Gal(beta1-4)Glc(beta1-1)Cer and AcNeu(alpha2-8)AcNeu(alpha2-3)Gal(beta1-4)Glc(beta1-1)Cer. The two main hexosamine-containing gangliosides are str...
متن کاملStudies on Platelet Proteins
T HE IMPORTANCE of blood platelets in hemostasis is now well established.’ Many of the physiologic properties of platelets suggest the presence of a contractile protein and Bettex-Galland and L#{252}scher ( 1961 ) succeeded in isolating such a contractile protein, thrombosthenin, and studied some of its properties.24 Grette ( 1962 ) confirmed the presence of this protein in pig platelets.5 Sinc...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1972
ISSN: 0021-9738
DOI: 10.1172/jci107078